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Mission: Impossible II of M:I-2 is een Amerikaanse actiefilm van John Woo uit 2000. De film is het vervolg op het succesvolle deel 1 van Mission Impossible uit de filmreeks. Wereldwijd bracht de film 546 miljoen dollar op.

Leeswaarschuwing: Onderstaande tekst bevat details over de inhoud of de afloop van het verhaal

Ethan Hunt (Tom Cruise) moet een dodelijk virus vernietigen, dat is ontwikkeld door een geneesmiddelenfabrikant. Deze geneesmiddelenfabrikant heeft het antigif in handen, waardoor de directeur enorm rijk zou worden. Wanneer ze aangekomen zijn bij het laboratorium waar het dodelijke virus zich bevindt, besluit een teamgenoot van Hunt, Nyah, zichzelf in te spuiten met het dodelijke virus, zodat zijzelf en de omgeving geen risico's oplopen. Hierna wordt Nyah gedropt in het midden van Sydney. Er volgt een race tegen de klok waarin Hunt zo snel mogelijk het antigif moet vinden en bezorgen bij Nyah.

De muziek van film werd gecomponeerd door Hans Zimmer, met uitgezonderd van de "Mission: Impossible Theme", die werd in de jaren zestig geschreven door Lalo Schifrin voor de televisieserie Mission: Impossible. De akoestische gitaar klanken die meerdere malen voorkomen tijdens de film werden gespeeld door Heitor Pereira. Er werd ook een soundtrack uitgebracht door Hollywood Records met de muziek van Limp Bizkit, Metallica, Foo Fighters en Brian May en de originele filmmuziek van Zimmer. De platenmaatschappij bracht een maand later nog een soundtrack uit met ditmaal alleen de muziek van Zimmer.

Metallica maakte voor Mission: Impossible II het lied 'I Disappear'.
Het nummer 'Take a Look Around (Theme from M:I-2)' van Limp Bizkit werd in Nederland en België een top
10-hit.

Mission: Impossible 2 (titled onscreen as Mission: Impossible II and abbreviated as M:i-2)[2] is a 2000 action spy film directed by John Woo, and produced by and starring Tom Cruise. It is a standalone sequel to Mission: Impossible (1996) and the second installment in the Mission: Impossible film series. The film also stars Dougray Scott, Thandiwe Newton, Richard Roxburgh, John Polson, Brendan Gleeson, Rade Šerbedžija and Ving Rhames. In the film, Ethan Hunt (Cruise) teams with professional thief Nyah Nordoff-Hall (Newton) to secure a genetically modified disease, Chimera, held by rogue Impossible Missions Force (IMF) agent Sean Ambrose (Scott), who is Nordoff-Hall's former lover.

Mission: Impossible 2 was theatrically released in the United States by Paramount Pictures on May 24, 2000, and grossed over $546 million worldwide, becoming the highest-grossing film of that year. It received mixed reviews from critics, with praise for the action sequences and Woo's direction, but criticism for the characterization. A third film, Mission: Impossible III, was released in 2006.

In Sydney, bio-genetics scientist Doctor Vladimir Nekhorvich sends a message to the IMF for Dimitri (Ethan Hunt's cover name), his old friend, warning that his employer, Biocyte Pharmaceuticals, forced him to develop a biological weapon, the Chimera virus, to profit from the cure, Bellerophon. He injects himself with the virus, carrying Bellerophon in a bag. However, en route to Atlanta, IMF agent Sean Ambrose, who was disguised as Dimitri, goes rogue, betrays Nekhorvich, using sleeping gas on everyone aboard, steals Bellerophon, and jumps out of the plane before it crashes into the Rockies.
In Seville, IMF director Swanbeck informs Ethan about Ambrose's actions, tasks him with recovering Chimera and Bellerophon, and has him recruit Nyah Nordoff-Hall, a professional thief and Ambrose's ex-girlfriend. Despite her initial reluctance, Ethan gets her to trace Ambrose to Sydney using an injectable tracking device. Ethan assembles his team, old friend and computer hacker Luther Stickell, and helicopter pilot Billy Baird in Sydney while Nyah pretends to rekindle her relationship with Ambrose.
After Ambrose uses a video of Chimera infecting one of Nekhorvich's colleagues to blackmail Biocyte's CEO, John McCloy, into cooperation, Nyah gives Ethan the memory card containing the video, revealing that Chimera has a 20-hour dormant period; Bellerophon is only effective if used within that window. Ethan's team kidnaps McCloy and learns that the only Bellerophon samples, taken by Nekhorvich, are now in Ambrose's hands, but he doesn't have the virus since Nekhorvich injected himself with it. Ethan breaks into Biocyte headquarters and destroys two samples of Chimera, but Ambrose's team ambushes him, having discovered Nyah's deception. At a stalemate, Ambrose orders Nyah to retrieve the virus' last sample, but she injects herself with it instead and begs Ethan to kill her to destroy the virus. Ethan refuses and flees the facility, promising to get her the cure.
Ambrose releases Nyah to wander the streets of Sydney, intending to start a pandemic. At Biocyte's storage facility on Bare Island, he offers to sell Bellerophon to McCloy in exchange for enough stock options to make him Biocyte's majority shareholder, enabling him and McCloy to make billions. Ethan infiltrates the base and fights Ambrose's right-hand man, Hugh Stamp; Stamp seemingly brings a subdued Ethan to Ambrose, who executes him. However, Ambrose, upon seeing Stamp's bandaged finger (which he had earlier cut with a cigar cutter for questioning his trust in Nyah), discovers that the dead "Ethan" is Stamp, masked and gagged, while the actual Ethan has stolen the Bellerophon samples. Enraged, Ambrose and his men chase Ethan onto the mainland; Hunt kills them, while Luther and Billy locate Nyah, who has wandered to a cliffside to kill herself and prevent the outbreak.
Ethan kills Ambrose in an extended fistfight on the beach and gives Bellerophon to the arriving Luther, who injects Nyah with it. In return for her cooperation, the IMF clears Nyah's criminal record, and Ethan starts a vacation with her in Sydney.

Tom Cruise as Ethan Hunt: An agent of the Impossible Missions Force (IMF).
Dougray Scott as Sean Ambrose: A rogue IMF agent who possesses Bellerophon.
Thandiwe Newton as Nyah Nordoff-Hall: A professional thief brought on to assist Ethan in tracing Ambrose.
Richard Roxburgh as Hugh Stamp: Ambrose's right-hand man.
John Polson as Billy Baird: A helicopter pilot.
Brendan Gleeson as John C. McCloy: CEO of Biocyte in Australia.
Rade Šerbedžija as Dr. Vladimir Nekhorvich: Creator of Chimera at Biocyte.
Ving Rhames as Luther Stickell: A computer hacker and IMF agent.
Additionally, Anthony Hopkins appears in an uncredited cameo appearance as Mission Commander Swanbeck.[6] Tom Cruise's cousin William Mapother and Dominic Purcell appear as, respectively, Wallis and Ulrich, two of Ambrose's henchmen.

William Goldman says he was the first writer on the film. "All that's left of mine is the climax... the climbing up the rocks sequence," he said. "I couldn't come up with a good villain and Bob Towne did."[7]
According to screenwriter Robert Towne, several action sequences were already planned for the film prior to his involvement and before the story had been written.[8] Ian McKellen was offered the part of Mission Commander Swanbeck, but turned it down.[9] Dougray Scott was cast in the film after he decided not to play the role of Wolverine in X-Men.[10]
Tom Cruise regretted killing off Jack Harmon in the previous film and attempted to include the character in the sequel. This idea was abandoned as Cruise and John Woo couldn't come up with a plausible way for Harmon to have survived his death in the previous film.[11]
Ronald D. Moore and Brannon Braga's draft of the script included Willy Armitage as one of the team members, though the role would have been recast with a younger actor instead of original cast member Peter Lupus.[12]
The studio expressed concern about the safety of filming Cruise's entrance scene, in which he is free solo climbing at Dead Horse Point State Park in Moab, Utah.[13] Cruise refused to drop the idea because he could not think of a better way to reintroduce the character. There was no safety net as he filmed the sequence, but he did have a harness and a thin wire.[14] He tore his shoulder when performing the jump from one part of the cliff to another.[15]
Thandiwe Newton discussed her unpleasant on-set experiences with Cruise during the shooting of the balcony sequence in a 2020 interview. According to Newton, Cruise was heavily stressed over the expectations of the sequel being good and was upset during the shooting of said scene because she had "the shittiest lines." The two decided to reverse roleplay each other as practice. However, it was unhelpful for her and pushed her "into a place of terror and insecurity." After the shooting was finished for the day, she contacted Jonathan Demme, telling him what happened. Looking back on that day, Newton said about Cruise, "Bless him. And I really do mean bless him because he was trying his damnedest".[16][17][18]
During the final fight scene between Ethan Hunt and Sean Ambrose, Cruise insisted that a real knife be used. The knife was attached to a cable and was carefully measured to stop a quarter of an inch from Cruise's eyeball, and Cruise asked Dougray Scott to put his full strength down on the knife to get a realistic look for the scene.
Music
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Main articles: Mission: Impossible 2 (score) and Mission: Impossible 2 (soundtrack)
The film's original score was composed by Hans Zimmer and features vocals performed by Lisa Gerrard.[19] In addition, the film includes contemporary music such as Limp Bizkit's rendition of Lalo Schifrin's Mission: Impossible theme entitled "Take a Look Around" as well as Metallica's "I Disappear".[20]
While Ethan is rock climbing during his holiday, Zap Mama's remixed version of "Iko Iko" plays on the soundtrack.
About the score, Zimmer said: "The love theme from Mission: Impossible [II] was written about 6 weeks before they started shooting. I was on it that early. Then, we had a big meeting in Australia. They had the love theme, and I knew what the story was about, and I always thought it was about these two men being in love with the girl. So I said to the record company guy, "Look, here's one thing I would love you to do, when you find bands for me, make them all female. Make them all about sirens." Of course, what did I get? A bunch of heavy metal bands with guys. I promise you, it would have been a better movie, and it would have been a better score."[21]
In 2024, Diego Pineda Pacheco from Collider singled out Mission: Impossible 2 as one of Zimmer's most underrated scores especially for the Injection scene: "The film's score is imbued with Spanish influences, filling the romance at the core of the narrative with passion and flair."